Canadian Practical Nurse Registration Examination (CPNRE) 2026 – 400 Free Practice Questions to Pass the Exam

Warfarin (Coumadin) is an anticoagulant medication that works by inhibiting the synthesis of vitamin K-dependent clotting factors in the liver. Vitamin K plays a crucial role in the coagulation process; it is essential for the production of certain proteins that are necessary for blood clotting. When Warfarin is administered, it decreases the availability of vitamin K, thereby reducing the formation of these clotting factors and leading to an anticoagulant effect.

Individuals taking Warfarin need to maintain consistent levels of vitamin K in their diet. Sudden changes in vitamin K intake can affect the drug's efficacy and impact the patient's INR (International Normalized Ratio) levels, which are monitored regularly to ensure the medication is working effectively to prevent blood clots while minimizing the risk of bleeding.

Vitamin A, vitamin C, and vitamin E are not directly involved in the coagulation process in the same way that vitamin K is, making them irrelevant in the context of Warfarin’s mechanism of action. Consequently, Warfarin specifically interferes with vitamin K, making it essential for patients on this medication to pay attention to their vitamin K intake and consult healthcare providers about dietary choices.