Canadian Practical Nurse Registration Examination (CPNRE) 2026 – 400 Free Practice Questions to Pass the Exam

Question: 1 / 595

What is a primary cause of schizophrenia?

Too much serotonin

Lack of norepinephrine

Too much dopamine

Schizophrenia is a complex mental disorder that is influenced by a variety of factors, including genetics, environment, and neurochemical imbalances. The role of dopamine has been particularly emphasized in the understanding of schizophrenia. It is believed that an excessive amount of dopamine activity, particularly in certain brain pathways, contributes significantly to the symptoms associated with the disorder, such as hallucinations, delusions, and disorganized thinking.

The dopamine hypothesis suggests that an increase in dopamine transmission in specific areas of the brain, such as the mesolimbic pathway, is linked to the positive symptoms of schizophrenia. This correlation has been supported by the efficacy of antipsychotic medications, which often work by blocking dopamine receptors, thereby reducing these symptoms.

While other neurotransmitters are also involved in the pathology of schizophrenia, the dominance of dopamine dysfunction in the current models of the disorder underscores why this particular answer is recognized as the primary cause. Understanding the balance of neurotransmitters and how their levels affect mental health can guide effective treatment strategies for individuals with schizophrenia.

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Low levels of GABA

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